Our lead scaffold for multifunctional RNA nanoparticles is the thermodynamically and chemically stable 3WJ 2’F-RNA motif of pRNA from phi29 DNA packaging motor. The stable 3WJ motif assembled from three short RNA oligos forms three helical branches. Functional RNA modules can be conjugated to all the three ends without affecting their folding and authentic functions.
Users can choose different functional modules (see above) to custom design your functional RNA nanoparticles. Up to three identical or different functional modules can be incorporated based on the customer needs.
Please consult our experts to custom-design RNA nanoparticles for your needs.